A CFD firefighter’s wife and three children were critically injured in a Montclare fire.

A house fire on Chicago’s Northwest Side on Tuesday night critically injured the wife and three children of an on-duty Chicago firefighter.

The fire broke out shortly after 9 p.m. in the 2500 block of North Rutherford Avenue, according to Chicago police.

Firefighters rescued a 34-year-old woman, two young girls, ages 2 and 7, and a 7-year-old boy who had all been exposed to smoke.

Stroger Hospital received an adult and two children.

According to Chicago fire officials, another child was transported to Community First Hospital.

According to CFD spokesman Larry Langford, the fire occurred at the home of an active Chicago firefighter who was on-duty at the time of the blaze.

According to Langford, the firefighter rushed to the scene after hearing his own address over the scanner.

A neighbor reported hearing a loud bang and looking out the window to see the house completely engulfed in flames. That’s when he called for assistance.

“I know there’s three children in the house and a mother,” John M. said.

The home’s damage was visible early Wednesday morning.

Fire inspectors have arrived to determine the cause of the fire.